(+)-Cloprostenol isopropyl ester CAS 157283-66-4

Identification
Properties
Safety Data
Specifications & Other Information
Links

Identification

CAS Number

157283-66-4

Name

(+)-Cloprostenol isopropyl ester

Synonyms

(5Z)-7-{(1R,2R,3R,5S)-2-[(3R)-4-(3-Chlorophénoxy)-3-hydroxy-1-butén-1-yl]-3,5-dihydroxycyclopentyl}-5-hepténoate d’isopropyle [French] [ACD/IUPAC Name]
5-Heptenoic acid, 7-[(1R,2R,3R,5S)-2-[(3R)-4-(3-chlorophenoxy)-3-hydroxy-1-buten-1-yl]-3,5-dihydroxycyclopentyl]-, 1-methylethyl ester, (5Z)- [ACD/Index Name]
Isopropyl (5Z)-7-{(1R,2R,3R,5S)-2-[(3R)-4-(3-chlorophenoxy)-3-hydroxy-1-buten-1-yl]-3,5-dihydroxycyclopentyl}-5-heptenoate [ACD/IUPAC Name]
Isopropyl-(5Z)-7-{(1R,2R,3R,5S)-2-[(3R)-4-(3-chlorphenoxy)-3-hydroxy-1-buten-1-yl]-3,5-dihydroxycyclopentyl}-5-heptenoat [German] [ACD/IUPAC Name]
(+)-9?,11?,15R-trihydroxy-16-(3-chlorophenoxy)-17,18,19,20-tetranor-prosta-5Z,13E-dien-1-oic acid, isopropyl ester
(+)-Cloprostenol isopropyl ester
157283-66-4 [RN]
ISOPROPYL CLOPROSTENATE

Molecular Structure

Structure of Cloprostenol isopropyl ester CAS 157283-66-4

Structure of Cloprostenol isopropyl ester CAS 157283-66-4

SMILES

CC(C)OC(=O)CCC/C=C\C[C@H]1[C@H](C[C@H]([C@@H]1C=C[C@H](COc2cccc(c2)Cl)O)O)O

StdInChI

InChI=1S/C25H35ClO6/c1-17(2)32-25(30)11-6-4-3-5-10-21-22(24(29)15-23(21)28)13-12-19(27)16-31-20-9-7-8-18(26)14-20/h3,5,7-9,12-14,17,19,21-24,27-29H,4,6,10-11,15-16H2,1-2H3/b5-3-,13-12?/t19-,21-,22-,23+,24-/m1/s1

StdInChIKey

OCNSAYQJDKJOLH-JSMWQALTSA-N

Molecular Formula

C25H35ClO6

Molecular Weight

466.99

Properties

Appearance

Colorless to Yellow oil

Safety Data

WGK Germany

3

Specifications and Other Information of Our (+)-Cloprostenol isopropyl ester CAS 157283-66-4

Standard

Enterprise standard

Identification Methods

HPLC

Purity

99% min

Water

1.0% max

Single Impurity

0.5% max

Total Impurities

1.5% max

Storage

2-8°C away from light

Application

The intermediate of Cloprostenol.
(+)-Cloprostenol is a synthetic analog of prostaglandin F2α (PGF2α). It is an FP receptor agonist and a potent luteolytic agent in rats and hamsters. (+)-Cloprostenol is the optically active, 15(R) enantiomer of cloprostenol responsible for the majority of its biological activity. It is 200 times more potent than PGF2α in terminating pregnancy when given subcutaneously at a daily dose of 0.125 μg/kg in rats and hamsters, without the side effects associated with PGF2α.1 (+)-Cloprostenol was also shown to be a potent inhibitor of rat adipose precursor differentiation in primary cultures with an IC50 value of 3 x 10-12 M.2 Cloprostenol isopropyl ester is a more lipid soluble form of cloprostenol.

General View of Documents

Cloprostenol isopropyl ester CAS 157283-66-4 HPLC

Cloprostenol isopropyl ester CAS 157283-66-4 HPLC

Links

This product is developed by our R&D company Caming Pharmaceutical Ltd(http://www.caming.com/), and here is the corresponding linkhttp://caming.com/cloprostenol-isopropyl-ester-cas-157283-66-4/

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Disclaimer

This product is for research and development purpose only which may not be used directly as drugs, food, cosmetics or for any other non-R&D purpose. It may be toxic or hazardous, and should be handled only by qualified individuals trained in laboratory procedures. The buyer will be responsible to warn and inform any person that may be in contact with the product of the potential risks and hazards, as well as to ensure that purchase, use and disposal of the product comply with local laws and regulations.