Watson-Int is an industry leader in custom synthesis services from milligram to ton scale and is an ideal organization for performing custom synthesis that is essential for your discovery and preclinical needs. Our team has experience with various chemical compounds including pharmaceuticals, key intermediates, metabolites and agrichemicals. Our specialized facilities can handle the most difficult of projects including chiral synthesis, stable isotopes and natural products. Our highly trained team of scientists is experienced in medicinal chemistry, process research and pilot plants.
Custom synthesis services include:
a. Small-Scale Synthesis
b. Synthesis of API and Intermediates
c. Large-Scale Manufacturing

In order to guarantee rapid and flexible processing of your requirements, we perform a project based approach.

Phase 1

The communication starts with the client contacting us. During this communication we define your intentions and needs as precisely as possible. In order to protect your interests a CDA is signed before we get into a deeper conversation and exchange of information.
When the technical package is submitted to us for internal review all departments involved will give feedback to that. Within 2 days we will decide whether Watson-Int is capable or not to support you with this enquiry.
When we are capable to support you our colleagues from our technical and R&D team will exchange information and ideas with you. Within 3 to 5 days Watson-Int delivers a quote with the required information, timelines and prices.

Phase 2

If you are happy with the outlined project we follow your placed order. A project manager will be appointed to head your project, manage your enquiry internally and will be responsible for keeping agreed timelines and milestones during the whole lifecycle of your project. The project manager will be your individual contact person.

We provide analytical services at all stages of the process. Our people are highly trained and we are fully equipped with state of the art analytical instrumentation, such as HPLC, GC, NMR, FT-IR, UV, heavy metals, loss on drying etc.

Acetylation	Acylation
Alkylation	Amidation
Ammonolysis	Bromination
Chlorination	Chloromethylation
Chlorosulfonation	Condensation
Cyclization	Dehalogenation
Dehydrohalogenation	Elimination
Esterification	Etherification
Formylation	Friedel-Carfts acylation
Fries rearrangement	Gabriel synthesis
Grignard reaction	Halide exchange
Hofmann degradation	Hydrogenation(catalytical)
Methylation	Newman-Kwart rearrangement
Nitration	Nitrosation
Oxidation	Phase transfer reaction
Reduction(Catalytical, metal hydrides)	Ring Fusion
Rosenmund reduction	Sandmeyer reaction
Saponification	Schotten-Baumann reaction
Substitution	Sulfation
Sulfonation	Transesterification
Vilsmeier reaction	Williamson ether synthesis