Polyinosinic–polycytidylic acid sodium salt CAS 42424-50-0

Custom Synthesis of Nucleotides
Identification
Properties
Safety Data
Specifications & Other Information
Links

Identification

CAS Number

42424-50-0

Name

Polyinosinic–polycytidylic acid sodium salt

Synonyms

Poly (I:C), Poly(I) • Poly(C)

Molecular Structure

structure of Polyinosinic–polycytidylic acid sodium salt CAS 42424-50-0

structure of Polyinosinic–polycytidylic acid sodium salt CAS 42424-50-0

Molecular Formula

(C19H21N7O14P2Na2)n

Molecular Weight

679.4

MDL Number

MFCD00131984

Properties

Appearance

White to off-white powder

Specifications and Other Information of Our Polyinosinic–polycytidylic acid sodium salt CAS 42424-50-0

Standard

Enterprise standard

Identification Methods

HPLC

Purity

95% min

pH

6.0-8.0

Transmissivity of solution

98% min

Loss on Drying

15.0% min

Sedimentation coefficient

4S min

Hyperchromic effect

55.0% min

Weight-average molecular weight

150-1000bp

Solubility

Freely soluble in water, insoluble in ethanol and ether.

Package

1kg

Manufacturing Capacity

200kg/year

Storage

Under room temperature away from light

Application

1. Application of human medicine: This product is an interferon inducer.Interferon induced by cell in vivo, the interferon effect on normal cells to produce anti-viral protein factor (AVF), thereby interfering with viral reproduction, protecting uninfected cells from viral infection. Therefore, this product has anti-viral, anti-tumor, and enhance immune function of lymphocytes and inhibition of nucleic acid metabolism effect. Clinic for chronic hepatitis B, epidemic hemorrhagic fever, epidemic encephalitis B, viral keratitis, herpes zoster, a variety of warts and respiratory infections. 2. Application of veterinary:mainly used in the prevention and treatment of poultry, livestock viral diseases. (1) It can be used with many drugs.When it compatibility with APS, levamisole or ribavirin , there are obvious synergies; Compatibility with some antibiotics,there have a synergistic or additive effect.When it is added in many varieties of flour, powder, etc,there has a significant role in improving the efficacy of existing products, but does not interfere with the detection of the original product; This product has no species specificity, and can be widely used on poultry, pigs, cattle and other animals . (2) As a vaccine adjuvant, when it is used with the vaccine simultaneously, can play to make up the immune blank period, relieve stress reaction of vaccines, enhance the role of the immune effects; drug residues can be avoided or reduced. (3) As a broad-spectrum antiviral drugs, it can be used: Chicken: infectious bronchitis, infectious laryngotracheitis, Newcastle disease, influenza, bursal disease, chicken pox. Duck: duck plague, duck viral hepatitis. Pigs: Pigs unnamed high fever (PRRS variants), PCV, PRRS, porcine reproductive and respiratory syndrome, porcine viral diarrhea, atypical swine fever.

Links

This product is developed by our R&D company Ulcho Biochemical Ltd(http://www.ulcho.com/), and here is the corresponding linkhttp://ulcho.com/polyinosinic-polycytidylic-acid-sodium-salt-cas-42424-50-0/

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Disclaimer

This product is for research and development purpose only which may not be used directly as drugs, food, cosmetics or for any other non-R&D purpose. It may be toxic or hazardous, and should be handled only by qualified individuals trained in laboratory procedures. The buyer will be responsible to warn and inform any person that may be in contact with the product of the potential risks and hazards, as well as to ensure that purchase, use and disposal of the product comply with local laws and regulations.